I plan on upping the ram for it and eventually following the guide that frees up space one you delete whatever standard apps you dont actually want.
I've got a toggle script that decides whether the machine goes into suspend mode on closing the screen, however, some people on the EEE forum are saying its better not to have the screen next to the keyboard when it gets hot (is this true? does it make a difference?)
I've gone into advanced desktop mode and installed Fluxbox to save some of that precious precious screen space

I've embedded an aterm console in the background and currently I use a run dialog to load all programs. I'd love for something like
Launchy: The Open Source Keystroke Launcher for Windows to come out, then I'll use that
Software wise, I've installed Opera however, every now and again it spikes; it does this on my work Gentoo box as well so i'm gonna stick with Firefox for now.
I also installed Xampp (well, LAMPP for linux) which is an all in one web server for mysql php etc. It's really handy with the type of work I'm doing.