The graphics on wow arent the most advanced but it is nearly 4 years old now and considering that its stood up surprisingly well.
Although the basic UI is a bit clunky there are loads of mods out there to completely change the UI.
Programs like bongos and titan panel can change the layout completely then there are plugins designed for specific classes that make things even better again. I am using somehting similar to this atm.
http://img392.imageshack.us/my.php?i...8232917zw7.jpg
Everything is easy to click with the mouse or as is the preference of myself and most wow players is bound to keys to make things even quicker.