Good news - connected HDD via magic bridge for a virus check & clean and it's now booting again in laptop.
Bad news - Avast antivirus won't run (and neither will upgrade to 5.0) due to a 'software restriction rule':
Access to C:\Program Files\Alwil Software\Avast5\AvastUI.exe has been restricted by your Administrator by location with policy rule {8aecd3ec-dc47-40ca-b645-0d18e64daccc} placed on path C:\Program Files\Alwil Software
Any ideas on how to lift the 'restriction'? Can only assume this is a result of the virus/malware.