Want to see the world's first AMD-based BTX system? Sadly, I can't quite show you that, but I did see something very close. Biostar's nForce4-based iDEQ 330P has something very close to picoBTX in terms of board layout. Being a small PC that doesn't support upgrade of the mainboard, the mainboard can have any layout that Biostar want. With their i915-based iDEQ a full picoBTX implementation, it seems they've designed the nForce4 version in much the same way. The CPU and core logic are lined up to take advantage of the iDEQ's cooling system, with the expansion slots and memory slots either side.
http://www.hexus.net/content/reviews...lld19JRD0xMDQ1