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Thread: AI platform helps bring to light a powerful new antibiotic

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    AI platform helps bring to light a powerful new antibiotic

    Halicin can kill some of the most dangerous antibiotic-resistant pathogens.
    Read more.

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    Re: AI platform helps bring to light a powerful new antibiotic

    An excellent use of AI, unlike that other fad of creating dinosaurs pffft
    Jon

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    Re: AI platform helps bring to light a powerful new antibiotic

    Interesting and well-written article - good to hear about tech's reach into important areas of life that can affect us all.

    This approach has to beat the current random scouring of caves and the sea-bed by scientists, all in the hope of stumbling across new naturally-occurring anti-biotics (without a lot of success, so far).

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    Re: AI platform helps bring to light a powerful new antibiotic

    To think all that processing which has gone into bitcoin could have figured this years ago.

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    Re: AI platform helps bring to light a powerful new antibiotic

    Fantastic!

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    Re: AI platform helps bring to light a powerful new antibiotic

    Quote Originally Posted by hexus
    It would have been interesting to find out what hardware / software the MIT researchers used to aid them in their task but nothing specific was mentioned in the news release, or when I dug further.
    Chemprop.
    https://github.com/chemprop/chemprop

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    Re: AI platform helps bring to light a powerful new antibiotic

    Quote Originally Posted by Percy1983 View Post
    To think all that processing which has gone into bitcoin could have figured this years ago.
    Just think of all the processing which has gone into this which could have gone into Bitcoin.

    Interestingly this is probably also a product of all that health data which has been given to Google to help with projects like this. To much whinging and whining.

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    Re: AI platform helps bring to light a powerful new antibiotic

    Quote Originally Posted by philehidiot View Post
    Interestingly this is probably also a product of all that health data which has been given to Google to help with projects like this. To much whinging and whining.
    Nope. This is a relatively simple application of machine learning, no human data involved other than existing reference sets of drugs approved for use and compound/toxicity databases.
    Last edited by kalniel; 21-02-2020 at 02:22 PM.

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    Re: AI platform helps bring to light a powerful new antibiotic

    Quote Originally Posted by kalniel View Post
    Nope. This is a relatively simple application of ML, no human data involved other than existing reference sets of drugs approved for use and compound/toxicity databases.
    Absolutely no reference to the large datasets of lab test results to see which other antibiotics are effective against which diseases? I find that unlikely but I'm open to being educated.

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    Re: AI platform helps bring to light a powerful new antibiotic

    Quote Originally Posted by philehidiot View Post
    Absolutely no reference to the large datasets of lab test results to see which other antibiotics are effective against which diseases? I find that unlikely but I'm open to being educated.
    They don't need human data to find out if an antibiotic works against a particular bacterial species. Remember they're not clinically trialing anything here, but they are selecting from pre-existing compounds. The drug they found is being investigated for diabetes for example.
    Last edited by kalniel; 21-02-2020 at 02:44 PM.

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    Re: AI platform helps bring to light a powerful new antibiotic

    And by relatively simple, I don't mean easy or not clever - primary neat bit in my opinion is how they represented molecules to train the neural network - previously neural nets have failed to be all that great at picking out relevant chemical structural features (I know, I tried to do them for protein molecules years ago), but these guys have found a way of representing the information that's useful. Once they've got that the classification bit is fairly normal, but then they've also done good investigative work in the lab trying to work out how the drug they've identified actually creates it's anti-bacterial effect, and therefore discover a novel action which might open the gates to further drug developments even by conventional means.

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    Re: AI platform helps bring to light a powerful new antibiotic

    OK, so how long before that AI decides humans are the highest threat pathogen on the planet?
    _______________________________________________________________________

    "Toss a coin to your Witcher,
    Oh valley of plenty,
    Oh valley of plenty,
    Ohh-hh-hh"

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    Re: AI platform helps bring to light a powerful new antibiotic

    Quote Originally Posted by Ttaskmaster View Post
    OK, so how long before that AI decides humans are the highest threat pathogen on the planet?
    If you ask the right (wrong) question, you'll get that answer

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    Re: AI platform helps bring to light a powerful new antibiotic

    Quote Originally Posted by kalniel View Post
    If you ask the right (wrong) question, you'll get that answer
    _______________________________________________________________________

    "Toss a coin to your Witcher,
    Oh valley of plenty,
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    Re: AI platform helps bring to light a powerful new antibiotic

    Quote Originally Posted by kalniel View Post
    If you ask the right (wrong) question, you'll get that answer
    Ah, but can you trust the answer even if you ask the right (wrong) question?

    HAL : I know I've made some very poor decisions recently, but I can give you my complete assurance that my work will be back to normal. I've still got the greatest enthusiasm and confidence in the mission. And I want to help you.

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    Re: AI platform helps bring to light a powerful new antibiotic

    ^nice link back to the name of the compound

    I used that line once with a boss I didn't get on with. They didn't get the reference (not that I was being serious, so probably a good thing)

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