Here's my 2c:
I have had WD for quite some time, and I'm very happy. Maxtor gave me no problems either. I really hate IBM/Hitachi, because I hade quite some problems with it (like not replying to motherboard correctly about being master/slave, not working with certain CD drives,....). And last, but not least, I've heard some really good comments about Samsung's drives. That's it, it's all up to you, and probably $ difference.