Using S3 for offsite backup

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Anyone out there using Amazon's S3 storage for backups? I'm considering using them for an offsite backup (still backing up to a USB disk and DVDs for local copies) for my home systems but there seem to be a fair few different packages about. I've done a fair amount of reading around but was wondering if anyone here has first hand experience of using it?

I'd be looking at around 40-50Gib of storage intially, which I should imagine growing by around 1Gib (actually around 600Mb, but best to err on the side of caution and all that) a month. The agent would need to be installed on a Server 2003 Standard box.

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Nobody? Ah well, I'll have a play and see how it goes. Might even get some sort of review together...