If you hunt around you should be able to find some reviews for crossfire setups, I'd expect. General wisdom is to always get the single fastest card you can afford. However, both nvidia and AMD have been working on improving framepacing and the overall experience of multi-gpu setups recently, which may be swinging the balance.
The obvious caveat to me is that crossfire setups duplicate data across the memory, so even if your 7850s have 4GB of RAM between them, they'll perform like a 2GB card in terms of memory usage (i think anyway, no doubt someone will correct me if I'm wrong). So if you want high res with lots of AA and other IQ processing, a single more powerful card is likely to be better.
All that said, crossfire very much does work, even at the very low end (I've got an HD3470/HD4200 hybrid crossfire setup that proves it
), and if you already had a 7850 and were considering adding a second it might be worth it. If you 're buying from scratch, though, I would bothered: I'd just get the best single card you can afford. After all, if it lasts long enough you could always buy a second one down the line...