Hopefully teh power draw would be split equally between the two rails. I would imagine a 20-22W rail would power it on its own. I think they are setting it high to compensate for the rest of peoples systems and safe guarding against a potential fire with a borderline system! Due to PCI limitations it is my understanding that this thing will not be able to draw more than 300W due to legal obligations. I do not think NV will start flaunting that.
My Corsair 550 has 41A on the 12V rail. I would be happy to run it on mine; whether it then turns my case into a baking inferno is another matter (oh and the price and availabilty).