Concrete evidence of what I keep telling people who love the GTX480 so much, with the exception of Crysis Warhead with 4xAA applied at 2560x1600 (irrelevant, as it's unplayable regardless, and this is only due to the game needing more than 1GB of GPU RAM) two 5850s are reliably, substantially better than one GTX480, and they still use less power and run cooler, both at idle and load. In a 3-slot spacing environment, they're probably still quieter too.
I'm going to try tackling PhysX on a new install when I swap my pair of 4870X2s for a 4GB HD5970, and stick a geforce in my second 16x slot, thinking about a GT240 or 9800GT, something in that region - hoping that's enough for 2560x1600. Would be willing to go up to a GTS250 if I can find one cheap, but that'd be about the limit. I'd ideally like to have a third GPU I can switch between hacked PhysX and tri-CF but I don't trust that sort of mod to be the least bit stable, and a third 5870, especially one with 2GB, which I'd really need to use, is a bit too pricey for my liking.