Does your RAM natively run at 2.1v? If so, running it at this will help stability... A LOT! Running on lower voltages will only cause yourself many headaches.
Keep the timings at 5-5-5-18... for now
Push the FSB to 400MHz, this will give you a 1600MHz quad-pumped FSB which is superior to pushing to 5-5-5-15
Push the CPU to 1.3v for now and run a test.