Don't waste your money on a 4600+ (or 4400+). The 4200+ is just as good for things that dual core CPUs do well, and much more reasonable on price.
I think it's a huge mistake to put an X2 in a Shuttle unless you use water-cooling and an external high quality PSU. If you do that though what is the advantage of a Shuttle? Nope, big mistake.
Unless you are buying the machine as a number cruncher or you must run multiple CPU intensive applications the X2 is not a good choice. The San Diego 3700+ and 4000+ would be much better.
I also wouldn't go FX-55. The FX-57 is here and the FX-55 will see a price reduction soon.