Assuming you're happy to spend the money on it - which I assume you are or you wouldn't have listed it - I'd get the 250GB Sammy 840. The noticable speed-up between SSDs and mechnical drives is from the faster random access times, not the sequential speeds, and Samsung have a good reputation for quality and relaibility in SSDs. With 250GB you won't really have to worry too much about what programs you're putting where - just make sure all your media files go on a hard drive and everything else can probably go on your SSD My HTPC had skyrim, X:COM, Torchlight 1 & 2, Dungeon Seige, TF2, and a few other games installed, and its only just ticked over 100GB. 250GB for programs should keep you going for ages