I dont see why not , the only reason why core 2 duo had to have thinbgs different was because of the FSB and voltages were lower than other boards.Originally Posted by ati
But for the quad its just same as core2 duomeaning the FSB, most likely it will be a bios fix.
Also agree with what pingu says , I forgot about the other chipsets but they will all support the E4200 , that i reckon will be better than the core 2 duo, time will tell.